What is CBG? (Cannabigerol)?
So, What is CBG? Cannabigerol (CBG) is one of many already identified cannabinoids in the cannabis plant. However, several people are familiar with cannabinoids, like tetrahydrocannabinol (THC) and cannabidiol (CBD).
Over the past 5 years, CBD has gained popularity on the mainstream media and the internet as a whole. Partly, this is due to the hype around medical health benefits. This has led to disdain for other cannabinoids extracted from cannabis. For instance, only a small percentage understand how CBG works. The limited knowledge of how Cannabigerol works has led to misinformation, which this article will debunk!
What is CBG?
CBG is an acronym for cannabigerol, one of the more than 100 cannabinoids extracted from cannabis. CBG cannabinoid is non-psychotic, which means it cannot get you high like tetrahydrocannabinol (THC). It is one of the cannabinoids classified as minor, accounting for less than 2% in hemp, and 1% in marijuana.
What is the source of CBG?
Cannabigerol occurs as cannabigerolic acid (CBGA). The CBGA is the base from which cannabinoids form and is found in cannabis trichomes. During the growth and maturity of the cannabis plant, the CBGA develops into other cannabinoids. When the CBGA is exposed to light or heat, it converts to CBG.
When was CBGA discovered?
Cannabigerol was first discovered over 50 years ago by researchers from Israel. It was not until 30 years ago when CBGA was found as the main compound from which the CBG formed. Due to the complex format of CBGA, few studies have taken place on the same. The only existing research has focused on how CBGA disintegrates to form THCA, the precursor to THC.
What are the potential medical benefits of CBGA?
Research findings have supported that CBGA could have the following health benefits:
Metabolic disorders– Clinical trials have proven that CBGA might help in the treatment of metabolic disorders. A clinical study showed that CBGA activates peroxisome proliferator-activated receptors (PPRAs), causing a drop in lipid accumulation. Although the study was carried out on computer simulation, it gave the green light to the possible application of CBGA on animals and humans.
Cardiovascular diseases– Studies carried out in vitro form have shown that CBGA might mitigate aldose reductase, the enzyme which results in oxidative stress. Management of oxidative stress reduces the possibility of getting heart infections. CBGA-infused treatment does not have adverse side effects, hence the perfect alternative to prescription drugs. When the drug is rolled out for human consumption, it will be a significant breakthrough.
Colon cancer– Colon cancer is the third most common type of cancer. It is also the fourth-largest cause of death for many cancer patients. An extract from the cannabis plant found that CBGA contained cytotoxic properties. The cytotoxic properties kill or hasten the demise of colon cancer cells. Further studies could form a breakthrough to the worrying colon cancer cases.
CBG vs. CBD: The Difference
The breakdown of CBGA results to CBDA, THCA, and CBG. The CBDA then breaks down further to form CBD. Although CBD and Cannabigerol are two different chemical compounds, they are both non-psychotic. However, the two cannabinoids manifest several varying effects. For instance, taking cannabis with high levels of CBG and CBD might reduce stress levels.
Lab experiments carried out on animals shows that Cannabigerol can increase appetite levels. This also results to decrease in weight level. On the other hand, CBD lowers appetite levels, resulting in a decrease in weight.
What are the benefits of CBG?
Several pieces of research carried out at clinical levels have shown the following potential health benefits of CBG:
1. CBG may relieve intraocular pressure and help treat glaucoma
Some medical trials have shown that taking THC can reduce the severity of glaucoma. Given that THC forms after the disintegration of CBGA. Earlier studies have also shown that a combination of CBG and other cannabinoids contained therapeutic benefits for the treatment of glaucoma. The studies have also demonstrated that Cannabigerol could help in the management of intraocular pressure. However, Cannabigerol is not prescribed as medication and can only be used as a supplement for the management of glaucoma.
Read: CBG and Glaucoma
2. It might help to manage colitis and inflammatory bowel disease.
Laboratory studies have shown that CBG can help suppress colitis. The study which was carried out in 2013 on rats showed that an intake of CBG reduced the severity of colitis. Taking cannabis has been claimed by some to reduce joint pain, abdominal pain, nausea, loss of appetite, and weight, which are associated with inflammatory bowel disease. Since marijuana contains more than 100 cannabinoids, it is still unclear if CBG alone could be the major solution.
3. CBG contains antibacterial properties
Preliminary studies carried out on CBG have shown that it contains antibacterial properties. Methicillin-resistant Staphylococcus Aureus (MRSA) is common bacteria that is drug-resistant, especially to methicillin.
Drug-resistance made MRSA fatal, hence the trial of alternative treatment options. However, several studies have proved that CBG could be a possible treatment for MRSA. For instance, clinical studies carried out in 2008 showed that CBG could reduce the severity of MRSA. Since CBG does not contain significant side effects, it can be infused into the treatment of MRSA and other similar infections.
4. CBG contributes to inhibition of GABA reuptake
GABA uptake is a significant cause of muscle tension and anxiety disorder. An intake of CBG causes the GABA intake to go down, leading to muscle relaxation, mental relief, and general calmness, both in the mind and body. Clinical studies carried out in 1975 showed that taking CBG reduced anxiety disorders, which is vital in the inhibition of GABA reuptake.
5. Possible management of Huntington’s and neurodegenerative diseases
Laboratory experiments carried out in 2015 on rats showed that CBG had the potential to suppress brain degeneration. The CBG was either applied as an isolate or as a broad CBG. Regardless of choice, the tests found that CBG reduced the level of brain degeneration. The CBG managed neurodegenerative diseases by changing the expression of abnormal cells.
6. Possible suppression of inflammation
Inflammation bowel disease (IBD) is the most common inflammation. Other conditions that are characterized by inflammation include psoriasis and eczema. Studies carried out on these conditions show that CBG plays a crucial role in their management. In the future, CBG could be infused in prescription drugs to manage the disease.
7. Improvement of skin health
The application of CBG oil on the skin can improve its health. For instance, CBG increases basal sebaceous lipid synthesis, which is vital in the management of acne. CBG is more effective than other cannabinoids such as CBD and THC. The increased synthesis in sebaceous lipids is also crucial in the control of dry skin, which exposes the skin to bacteria.
CBG skincare suppresses inflammation caused by conditions such as rosacea and psoriasis. CBG can also help in the management of certain forms of skin cancer.
Check out this article: CBD Topics for Dry Skin
What are the potential medical benefits of CBD?
CBD remains the most common non-psychotic chemical compound. Partly, this is due to the large composition, especially in the hemp plant. CBD is also famous for the following health benefits:
a) Anti-seizure properties
Preliminary studies on CBD have shown that it is useful in the suppression of epilepsy. Clinical studies carried out on patients suffering from seizures showed that taking CBD reduced the severity and frequency of attacks.
An experiment was carried out in 2016 to determine the effectiveness of CBD in the treatment of seizures. During the study, 214 epileptic people participated, taking between 2 and 5mg of CBD every day for 12 weeks. After the expiry of the period, 36.5% of the participants had incurred fewer attacks. On the other hand, the intensity of seizures had dropped significantly in12% of the participants.
b) Management of chronic pain
CBD interacts indirectly with CB2 receptors, activating them to produce endocannabinoids. The endocannabinoids trigger nerves in the ECS, causing the brain receptors to suppress chronic pain. The anti-inflammatory features make CBD a good alternative natural therapy during chemotherapy.
Injured athletes are often taking CBD to speed up the healing process. It is also worth noting that CBD is infused into Sativex, a prescription drug for pain management. This is evidence that CBD is slowly inching its way into the mainstream.
c) Anxiety relief
According to researchers, CBD might interfere with the serotine, the hormone which controls how the body reacts to anxiety. CBD can help to suppress stress in the following ways:
- Inducing sleep, which allows the brain to relax.
- Suppressing post-traumatic stress disorder (PTSD)
- Lowering stress levels
d) Neuroprotective properties
CBD activates brain receptors, which in turn suppresses the degeneration of brain cells. Studies are still underway to determine how CBD helps in the management of the following degenerative conditions:
- Multiple sclerosis
- Alzheimer’s Disease
- Parkinson’s Disease
Which are the best CBG hemp strains?
The partial research results on CBG have increased the demand for the cannabinoids. The following cannabis strains are rich in CBG:
Lemon cream diesel– lemon cream is rich in sweet citrus and lemon flavors. It is revered for its calming effects, which is effective in the management of chronic pain. Lemon cream also contains relatively high CBG levels.
Jack Frost CBG– It a hybrid of between Northern Lights #5, Rainbow Kashmiri, White Widow, and Jack Herer. It has a smooth and sweet flavor with a hoppy citrus aroma. Other notable features in this cannabis strain an aroma and taste of pine and chamomile. Studies carried out have shown that the strain can contain up to 18% of CBG.
White CBG– This cannabis strain is extracted from the “The White” cannabis strain. Unlike the predecessor, this White CBG does not contain THC. The strain has an aroma of lemon and a flavor of hash and cream.
Superglue CBG– Superglue CBG is famous for its green and purple leaves. The CBG levels are high, making it one of the strains with high demand.
Stem cell CBG– Stem cell CBG was the first cannabis strain to be commercialized. This resin strain does not have a sweet flavor or aroma. Nevertheless, it is one of the highly potent strains, with some buds containing up to 99% of Cannabigerol.
FAQs on CBG
Studies about Cannabigerol are still in infant stages. As a result, several questions have emerged concerning their effects, legality, and potency. Here are the most frequently asked questions:
Can CBD and CBG be used together?
Infusing Cannabigerol to CBD is possible. The two cannabinoids increase the potency of the entourage effect.
Is CBG legal?
The Farm Bill of 2018 decriminalized products extracted from hemp, which CBG is one of them. However, the legalization was on the federal level alone. Each state has its unique laws governing the consumption and possession of CBG.
Can you get high from using CBG?
CBG does not give a head-high effect. Instead, it counteracts with THC to provide calming effects.
Why is CBG expensive?
CBG is referred to as the “Rolls Royce” of cannabinoids due to its high costs. The extraction of Cannabigerol from cannabis is complicated and requires a lot of expertise, which makes it expensive. Besides, the rising demand for CBG makes it pricey.
What are the side effects of CBG oil?
Each human body reacts uniquely when something new gets introduced into its system. Some people experience several side effects after consuming CBG oil. Most of these side effects are short-lived. The most common side effects include:
- Dry mouth
- Changes in appetite and weight
If the side effects persist, it is advisable to discontinue using the dosage and seek medical attention.
CBG and CBD: Which one is better?
Cannabigerol is similar to CBD in many aspects. However, each cannabinoid has pros and cons.
The two cannabinoids share many similarities, making them effective supplements. When buying CBD or CBG oil, it is advisable to perform your due diligence in researching the companies. At Come Back Daily, product transparency is very important. Always consult with your doctor or physician when adding anything new to your daily routine.